"The groundwork of all happiness is health." - Leigh Hunt

New blood test for colon cancer with high accuracy within the test

March 14, 2024 – Detecting colon cancer could at some point be as easy as an easy blood test.

Promising results from this recent option – the outcomes of the study were published this week within the New England Journal of Medicine — could help convert the estimated 1 in 3 people who find themselves uninformed about health screenings that ought to begin at age 45. If everyone within the U.S. got regular screenings, as much as 90% of deaths from colorectal cancer might be avoided, the researchers wrote. Current screening options are sometimes perceived as unpleasant experiences—collecting a stool sample at home and mailing it, or taking laxatives and being sedated for a colonoscopy.

The blood test can detect DNA released into the bloodstream by tumors and in a Attempt In greater than 7,800 people, the brand new test was capable of accurately detect colon cancer in early, treatable stages in 87% of cases. The false positive rate was 10%. The test was less successful in detecting advanced precancerous lesions, detecting only 13%. In comparison, stool tests are about 42% successful in early detection and colonoscopies are as much as 93% accurate, in keeping with a summary of the American College of Surgeons.

Colon cancer is the second leading reason behind cancer death within the United States and some of the common cancers overall. Each 12 months, greater than 150,000 persons are diagnosed nationwide, and greater than 50,000 people die from colon or rectal cancer annually.

According to a bunch of physicians who focus on diseases of the gastrointestinal tract, early detection within the precancerous stage is a crucial consideration.

“While a blood test can be an additional tool, it should not be used in place of a colonoscopy,” he said opinion really helpful by the American Gastroenterological Association.

“Colonoscopies allow for the detection and removal of precancerous polyps, as well as early detection of cancer when it is in the most treatable stages. The blood test reports in the New England Journal of Medicine The study is only intended to detect cancers and not precancerous polyps.”

Current Screening guidelines For people at average risk, suggest a colonoscopy every 10 years or an annual stool exam.

The recent blood test can be performed every three years and might be considered for FDA approval this 12 months, in keeping with manufacturer Guardant Health, NBC News reports reported.